Population Pharmacokinetic Model for Cancer Chemoprevention With Sulindac in Healthy Subjects

Author:

Berg Alexander K.1,Mandrekar Sumithra J.1,Ziegler Katie L. Allen1,Carlson Elsa C.1,Szabo Eva2,Ames Mathew M.1,Boring Daniel2,Limburg Paul J.1,Reid Joel M.1,

Affiliation:

1. Mayo Clinic; Rochester, MN; USA

2. Division of Cancer Prevention, National Cancer Institute; National Institutes of Health; Bethesda, MD; USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference38 articles.

1. Sulindac DRUGDEX® System [Internet database] Greenwood Village, Colo Thomson Reuters (Healthcare) Inc

2. Chemoprevention strategies using NSAIDs and COX-2 inhibitors;Keller;Cancer Biol Ther.,2003

3. Clinical pharmacokinetics of sulindac. A dynamic old drug;Davies;Clin Pharmacokinet.,1997

4. Studies on the metabolism and biological activity of the epimers of sulindac;Brunell;Drug Metab Dispos.,2011

5. Identification of the biologically active form of sulindac;Duggan;J Pharmacol Exp Ther.,1977

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