Optimization of Jiuzao protein hydrolysis conditions and antioxidant activity in vivo of Jiuzao tetrapeptide Asp-Arg-Glu-Leu by elevating the Nrf2/Keap1-p38/PI3K-MafK signaling pathway-Reference-Cited by-同舟云学术

Optimization of Jiuzao protein hydrolysis conditions and antioxidant activity in vivo of Jiuzao tetrapeptide Asp-Arg-Glu-Leu by elevating the Nrf2/Keap1-p38/PI3K-MafK signaling pathway

Published:2021 Issue:11 Volume:12 Page:4808-4824
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Jiang Yunsong¹²³⁴⁵^ORCID,Wang Rui¹²³⁴,Yin Zhongtian⁵⁶⁷⁴⁸,Sun Jinyuan⁵⁶⁷⁴^ORCID,Wang Bowen⁵⁶⁷⁴,Zhao Dongrui⁵⁶⁷⁴^ORCID,Zeng Xin-an⁸⁹¹⁰⁴,Li Hehe⁵⁶⁷⁴,Huang Mingquan⁵⁶⁷⁴^ORCID,Sun Baoguo⁵⁶⁷⁴

Affiliation:

1. School of Food Science and Engineering

2. South China University of Technology

3. 510640 Guangzhou

4. China

5. Beijing Laboratory of Food Quality and Safety

6. Beijing Technology and Business University

7. Beijing 100048

8. College of Food Science and Nutritional Engineering

9. China Agricultural University

10. Beijing

Abstract

Tetrapeptide DREL from Jiuzao exhibits antioxidant and anti-inflammatory activities through activating the Nfr2/Keap1-p38/PI3K-MafK signaling pathway and downstream antioxidant enzymes.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02852E

Reference48 articles.

1. Optimization of pea protein hydrolysate preparation and purification of antioxidant peptides based on an in silico analytical approach

2. Identification of a novel ACE-inhibitory peptide from casein and evaluation of the inhibitory mechanisms