Incidence of the melting-degradation process of vitamin C on the determination of the phase diagram with acetaminophen enhanced by high performance liquid chromatography tools
Author:
Affiliation:
1. Unité de Technologies Chimiques et Biologiques pour la Santé
2. Inserm U 1022 CNRS UMR 8258
3. Faculté des Sciences Pharmaceutiques et Biologiques
4. Université Paris Descartes
5. 75006 Paris
6. Sorbonne Paris Cité
7. France
Abstract
The exact solid–liquid equilibrium between ascorbic acid and acetaminophen was established combining high performance liquid chromatography and differential scanning calorimetry.
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2015/NJ/C4NJ01766H
Reference6 articles.
1. DSC study and phase diagrams calculation of binary systems of paracetamol
2. The role of stearic acid in ascorbic acid protection from degradation: a heterogeneous system for homogeneous thermodynamic data
3. Degradation of Ascorbic Acid in Aqueous Solution
4. Polymorphism of paracetamol: Relative stabilities of the monoclinic and orthorhombic phases inferred from topological pressure‐temperature and temperature‐volume phase diagrams
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