Synthesis of substituted benzo[b][1,4]oxazepine derivatives by the reaction of 2-aminophenols with alkynones-Reference-Cited by-同舟云学术

Synthesis of substituted benzo[b][1,4]oxazepine derivatives by the reaction of 2-aminophenols with alkynones

Published:2020 Issue:3 Volume:18 Page:415-419
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Oshimoto Kohei¹²³⁴⁵,Zhou Biao¹²³⁴⁵^ORCID,Tsuji Hiroaki¹²³⁴⁵^ORCID,Kawatsura Motoi¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. College of Humanities & Sciences

3. Nihon University

4. Tokyo 156-8550

5. Japan

Abstract

We have developed a novel synthetic method accessing benzo[b][1,4]oxazepines that are one of the rare classes of benzoxazepine derivatives by reaction of 2-aminophenols with alkynones in 1,4-dioxane at 100 °C.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/C9OB02450F

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2. Nonsteroidal antiinflammatory agents. 1. 10,11-Dihydro-11-oxodibenz[b,f]oxepinacetic acids and related compounds

3. Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 2. Tricyclic pyridobenzoxazepinones and dibenzoxazepinones

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