Efficient polymerase chain reaction assisted by metal–organic frameworks

Author:

Sun Chunli12345ORCID,Cheng Yong6345ORCID,Pan Yong12345,Yang Juliang78945,Wang Xudong12345,Xia Fan12345ORCID

Affiliation:

1. Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica

2. School of Chemistry and Chemical Engineering

3. Huazhong University of Science and Technology

4. Wuhan 430074

5. China

6. School of Materials Science and Engineering

7. Engineering Research Center of Nano-Geomaterials of Ministry of Education

8. Faculty of Materials Science and Chemistry

9. China University of Geosciences

Abstract

Many new materials have the ability to optimize polymerase chain reaction (PCR). Metal-organic frame materials UiO-66 and ZIF-8 can enhance sensitivity, specificity and efficiency of PCR, indicating their potential as PCR enhancers.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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