A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior-Reference-Cited by-同舟云学术

A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior

Published:2017 Issue:58 Volume:53 Page:8156-8159
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Jacob NIcholas T.¹²³⁴⁵,Anraku Kensaku¹²³⁴⁵,Kimishima Atsushi¹²³⁴⁵,Zhou Bin¹²³⁴⁵,Collins Karen C.¹²³⁴⁵,Lockner Jonathan W.¹²³⁴⁵,Ellis Beverley A.¹²³⁴⁵,Janda Kim D.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry, Department of Immunology and Microbial Science

2. The Skaggs Institute for Chemical Biology

3. The Worm Institute for Research and Medicine (WIRM)

4. The Scripps Research Institute

5. La Jolla

Abstract

A bioconjugate targeted to prefromed, xenoreactive antibodies also containing a cocaine hapten elicits a potent and specific anti-cocaine response able to significantly attenuate cocaine-induced behavior.

Funder

National Center for Advancing Translational Sciences

National Institute on Drug Abuse

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CC/C7CC04055E

Reference35 articles.

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2. European Monitoring Centre for Drugs and Drug Addiction European Drug Report 2016: Trends and Developments; Publications Office of the European Union: Luxembourg, 2016

3. Center for Behavioral Health Statistics and Quality Behavioral Health Trends in the United States: Results from the 2014 National Survey on Drug Use and Health 2015. (HHS Publication No. SMA 15-4927, NSDUH Series H-50) Retrieved from http://www.samhsa.gov/data/

4. National Institute on Drug Abuse. Cocaine 2016

5. Vaccines targeting drugs of abuse: is the glass half-empty or half-full?

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