Tunable synthesis of α,β-multifunctionalized azaheterocycles <i>via</i> the cascade reaction of saturated cyclic amines with diverse nucleophiles promoted by oxoammonium salt-Reference-Cited by-同舟云学术

Tunable synthesis of α,β-multifunctionalized azaheterocycles via the cascade reaction of saturated cyclic amines with diverse nucleophiles promoted by oxoammonium salt

Published:2023 Issue:5 Volume:10 Page:1206-1212
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

He Yan¹^ORCID,Liu Qimeng¹,Gong Tian¹,Liu Yunfei²,Zhang Xinying¹^ORCID,Fan Xuesen¹^ORCID

Affiliation:

1. NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Key Laboratory for Yellow River and Huai River Water Environmental Pollution Control, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Environment, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China

2. The 22nd Research Institute of China Electronics Technology Group Corporation, Xinxiang, Henan 453003, China

Abstract

Herein we have developed a convenient method for the tunable synthesis of α,β-multifunctionalized azaheterocycles via the oxoammonium salt promoted cascade reaction of saturated cyclic amines with different nucleophiles.

Funder

Science and Technology Innovation Talents in Universities of Henan Province

National Natural Science Foundation of China

Henan Key Laboratory of Organic Functional Molecules and Drug Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO01427K

Reference39 articles.

1. Potent Antimalarial Febrifugine Analogues against the Plasmodium Malaria Parasite

2. Synthesis and Biological Evaluation of NK1 Antagonists Derived from L-Tryptophan

3. 4,4-Disubstituted Piperidines: A New Class of NK1 Antagonists

4. New Synthetic Technologies for the Construction of Heterocycles and Tryptamines

5. Pivotal Role of an Aliphatic Side Chain in the Development of an HDM2 Inhibitor

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