Organocatalytic asymmetric [3 + 3] annulations of 3-carboxamide oxindoles with β,γ-unsaturated α-keto esters: facile access to chiral spiro-δ-lactam oxindoles-Reference-Cited by-同舟云学术

Organocatalytic asymmetric [3 + 3] annulations of 3-carboxamide oxindoles with β,γ-unsaturated α-keto esters: facile access to chiral spiro-δ-lactam oxindoles

Published:2023 Issue:4 Volume:10 Page:957-962
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhang Zheng-Bing¹^ORCID,He Qiuzuo¹,Wang Ting¹,Wang Guoqin¹,Yang Dan¹,Han Pan¹,Jing Linhai¹^ORCID

Affiliation:

1. Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, China West Normal University, Nanchong 637002, P. R. China

Abstract

A novel strategy for the organocatalytic asymmetric synthesis of spiro-δ-lactam oxindoles was developed via a [3 + 3] annulation of 3-carboxamide oxindoles and β,γ-unsaturated α-keto esters with excellent diastereoselectivities and enantioselectivities.

Funder

Sichuan Province Science and Technology Support Program

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO01423H

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