2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach

Author:

Schehr Miriam1234,Ianes Chiara5674,Weisner Jörn89104,Heintze Linda11234,Müller Matthias P.89104ORCID,Pichlo Christian1213144,Charl Julia1213144,Brunstein Elena1213144,Ewert Julia1234,Lehr Marc1234,Baumann Ulrich1213144,Rauh Daniel89104ORCID,Knippschild Uwe5674,Peifer Christian11234ORCID,Herges Rainer1234

Affiliation:

1. Otto Diels-Institute of Organic Chemistry

2. Christian Albrechts University Kiel

3. 24118 Kiel

4. Germany

5. Department of General and Visceral Surgery

6. Ulm University Hospital

7. 89081 Ulm

8. Faculty of Chemistry and Chemical Biology

9. TU Dortmund University and Drug Discovery Hub Dortmund (DDHD) am Zentrum für integrierte Wirkstoffforschung (ZIW)

10. Dortmund

11. Institute of Pharmacy

12. Department of Chemistry

13. University of Cologne

14. 50674 Cologne

Abstract

The synthesis and characterization of new photoswitchable kinase inhibitors is reported.

Funder

Deutsche Forschungsgemeinschaft

Universität Ulm

Bundesministerium für Bildung und Forschung

European Regional Development Fund

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3