A high-affinity, cis-on photoswitchable beta blocker to optically control β2-adrenergic receptors in vitro and in vivo

Author:

Shi ShuangORCID,Zheng Yang,Goulding Joëlle,Marri Silvia,Lucarini Laura,Konecny Benjamin,Sgambellone Silvia,Villano Serafina,Bosma Reggie,Wijtmans Maikel,Briddon Stephen J.,Zarzycka Barbara A.,Vischer Henry F.,Leurs RobORCID

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

China Scholarship Council

Publisher

Elsevier BV

Reference40 articles.

1. Optical control of Class A G protein-coupled receptors with photoswitchable ligands;Wijtmans;Curr. Opin. Pharmacol.,2022

2. On the Promise of Photopharmacology Using Photoswitches: A Medicinal Chemist’s Perspective;Fuchter;J. Med. Chem.,2020

3. Photopharmacology of G Protein-coupled receptors;Panarello,2022

4. GPCR photopharmacology;Ricart-Ortega;Mol. Cell. Endocrinol.,2019

5. Reversible photocontrol of biological systems by the incorporation of molecular photoswitches;Szymański;Chem. Rev.,2013

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