Triazole-based, optically-pure metallosupramolecules; highly potent and selective anticancer compounds-Reference-Cited by-同舟云学术

Triazole-based, optically-pure metallosupramolecules; highly potent and selective anticancer compounds

Published:2020 Issue:47 Volume:56 Page:6392-6395
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Song Hualong¹²³⁴^ORCID,Rogers Nicola J.¹²³⁴^ORCID,Brabec Viktor⁵⁶⁷⁸^ORCID,Clarkson Guy J.¹²³⁴^ORCID,Coverdale James P. C.¹²³⁴^ORCID,Kostrhunova Hana⁵⁶⁷⁸^ORCID,Phillips Roger M.⁹¹⁰¹¹⁴^ORCID,Postings Miles¹²³⁴^ORCID,Shepherd Samantha L.⁹¹⁰¹¹⁴^ORCID,Scott Peter¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Warwick

3. Coventry CV4 7AL

4. UK

5. The Czech Academy of Sciences

6. Institute of Biophysics

7. CZ-61265 Brno

8. Czech Republic

9. School of Applied Sciences

10. University of Huddersfield

11. Huddersfield

Abstract

Click-derived functionalised triazoles self-assemble to water-compatible, optically pure, low symmetry metallohelices that display sub-micromolar antiproliferative activity, excellent selectivity and synergistic combination with cisplatin.

Funder

University of Warwick

China Scholarship Council

Grantová Agentura České Republiky

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC02429E

Reference30 articles.

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4. Building on architectural principles for three-dimensional metallosupramolecular construction

5. Self-assembly of tetravalent Goldberg polyhedra from 144 small components

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