Transition-metal-free radical relay cyclization of vinyl azides with 1,4-dihydropyridines involving a 1,5-hydrogen-atom transfer: access to α-tetralone scaffolds-Reference-Cited by-同舟云学术

Transition-metal-free radical relay cyclization of vinyl azides with 1,4-dihydropyridines involving a 1,5-hydrogen-atom transfer: access to α-tetralone scaffolds

Published:2020 Issue:22 Volume:7 Page:3638-3647
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liao Yangzhen¹²³⁴⁵,Ran Yu¹²³⁴⁵,Liu Guijun¹²³⁴⁵,Liu Peijun¹²³⁴⁵,Liu Xiaozu¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province

2. Generic Drug Research Center of Guizhou Province

3. School of Pharmacy

4. Zunyi Medical University

5. Zunyi 563000

Abstract

The remote C(sp³)–H functionalization enabled by a radical-mediated 1,5-hydrogen-atom transfer (HAT) process using vinyl azides and 1,4-dihydropyridines as precursors has been described.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO01042A

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