Isoamphipathic antibacterial molecules regulating activity and toxicity through positional isomerism-Reference-Cited by-同舟云学术

Isoamphipathic antibacterial molecules regulating activity and toxicity through positional isomerism

Published:2023 Issue:18 Volume:14 Page:4845-4856
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Barman Swagatam¹,Mukherjee Sudip¹,Jolly Logia¹,Troiano Cassandra²,Grottesi Alessandro³,Basak Debajyoti¹,Calligari Paolo²^ORCID,Bhattacharjee Brinta¹,Bocchinfuso Gianfranco²^ORCID,Stella Lorenzo²^ORCID,Haldar Jayanta¹⁴^ORCID

Affiliation:

1. Antibacterial Research Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore, 560064, India

2. Department of Chemical Science and Technologies, University of Rome Tor Vergata, via della Ricerca Scientifica, 1, 00133, Rome, Italy

3. Cineca, Via dei Tizii, 6, 00185, Rome, Italy

4. School of Advanced Materials, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore, 560064, India

Abstract

Peptidomimetic antimicrobials exhibit a selective interaction with bacterial cells over mammalian cells once they have achieved an optimum amphiphilic balance (hydrophobicity/hydrophilicity) in the molecular architecture.

Funder

Indo-French Centre for the Promotion of Advanced Research

Department of Biotechnology, Ministry of Science and Technology

Jawaharlal Nehru Centre for Advanced Scientific Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D2SC06065E

Reference40 articles.

1. Tackling antibiotic resistance