First total synthesis of chromanone A, preparation of related compounds and evaluation of their antifungal activity against Candida albicans, a biofilm forming agent-Reference-Cited by-同舟云学术

First total synthesis of chromanone A, preparation of related compounds and evaluation of their antifungal activity against Candida albicans, a biofilm forming agent

Published:2021 Issue:32 Volume:11 Page:19587-19597
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cortés Iván¹²³⁴⁵^ORCID,Cordisco Estefanía⁶²³⁴⁵^ORCID,Kaufman Teodoro S.¹²³⁴⁵^ORCID,Sortino Maximiliano A.⁶²³⁴⁵^ORCID,Svetaz Laura A.⁶²³⁴⁵^ORCID,Bracca Andrea B. J.¹²³⁴⁵^ORCID

Affiliation:

1. Instituto de Química Rosario (IQUIR, CONICET-UNR)

2. Facultad de Ciencias Bioquímicas y Farmacéuticas

3. Universidad Nacional de Rosario

4. S2002LRK Rosario

5. Argentina

6. Area Farmacognosia

Abstract

Chromanone A and its 7-OMe analogue were totally synthesized. 2-Formyl chromanone A derivative inhibited C. albicans and its virulence factors.

Funder

Fondo para la Investigación Científica y Tecnológica

Consejo Nacional de Investigaciones Científicas y Técnicas