Baseline toxicity and ion-trapping models to describe the pH-dependence of bacterial toxicity of pharmaceuticals-Reference-Cited by-同舟云学术

Baseline toxicity and ion-trapping models to describe the pH-dependence of bacterial toxicity of pharmaceuticals

Published:2017 Issue:7 Volume:19 Page:901-916
ISSN:2050-7887
Container-title:Environmental Science: Processes & Impacts
language:en
Short-container-title:Environ. Sci.: Processes Impacts

Author:

Baumer Andreas¹²³⁴⁵,Bittermann Kai¹²³,Klüver Nils¹²³,Escher Beate I.¹²³⁶⁷^ORCID

Affiliation:

1. Helmholtz Centre for Environmental Research – UFZ

2. DE-04318 Leipzig

3. Germany

4. Department of Clinical Pharmacy

5. Leipzig University

6. Eberhard Karls University Tübingen

7. Environmental Toxicology

Abstract

The pH-dependence of cytotoxicity of diverse acidic, basic and multiprotic pharmaceuticals could be explained by baseline toxicity after invoking mixture effects of all species and delayed uptake of charged species.

Publisher

Royal Society of Chemistry (RSC)

Subject

Management, Monitoring, Policy and Law,Public Health, Environmental and Occupational Health,Environmental Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/EM/C7EM00099E

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