LogD-based modelling and ΔlogD as a proxy for pH-dependent action of ionizable chemicals reveal the relevance of both neutral and ionic species for fish embryotoxicity and possess great potential for practical application in the regulation of chemicals
Author:
Funder
Umweltbundesamt
Publisher
Elsevier BV
Subject
Pollution,Waste Management and Disposal,Water Science and Technology,Ecological Modeling,Environmental Engineering,Civil and Structural Engineering
Reference45 articles.
1. Predictability of the toxicity of multiple chemical mixtures to Vibrio fischeri: mixtures composed of similarly acting chemicals;Altenburger;Environ. Toxicol. Chem.,2000
2. pH-metric logP 10. Determination of liposomal membrane-water partition coefficients of ionizable drugs;Avdeef;Pharm. Res.,1998
3. Baseline toxicity and ion-trapping models to describe the pH-dependence of bacterial toxicity of pharmaceuticals;Baumer;Environ. Sci. Process Impacts,2017
4. Prediction of phospholipid−water partition coefficients of ionic organic chemicals using the mechanistic model COSMOmic;Bittermann;J. Phys. Chem. B,2014
5. Influence of pH on the uptake and toxicity of β-blockers in embryos of zebrafish, Danio rerio;Bittner;Aquat. Toxicol.,2018
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Aquatic thresholds for ionisable substances, such as diclofenac, should consider pH-specific differences in uptake and toxicity;Science of The Total Environment;2024-01
2. Facilitating structural elucidation of small environmental solutes in RPLC-HRMS by retention index prediction;Chemosphere;2023-10
3. Liver and Plasma Concentrations of Food Chemicals after Virtual Oral Doses Extrapolated Using <i>in Silico</i> Estimated Input Pharmacokinetic Parameters to Confirm Reported Liver Toxicity in Rats;Biological and Pharmaceutical Bulletin;2023-08-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3