Seventeen novel angiotensin converting enzyme (ACE) inhibitory peptides from the protein hydrolysate of <i>Mytilus edulis</i>: isolation, identification, molecular docking study, and protective function on HUVECs-Reference-Cited by-同舟云学术

Seventeen novel angiotensin converting enzyme (ACE) inhibitory peptides from the protein hydrolysate of Mytilus edulis: isolation, identification, molecular docking study, and protective function on HUVECs

Published:2022 Issue:14 Volume:13 Page:7831-7846
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Suo Shi-Kun¹,Zhao Yu-Qin¹,Wang Yu-Mei¹,Pan Xiao-Yang²,Chi Chang-Feng²,Wang Bin¹^ORCID

Affiliation:

1. Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China

2. National and Provincial Joint Laboratory of Exploration and Utilization of Marine Aquatic Genetic Resources, National Engineering Research Center of Marine Facilities Aquaculture, School of Marine Science and Technology, Zhejiang Ocean University, Zhoushan 316022, China

Abstract

This study suggested that bioactive peptides from blue mussel could serve as a therapeutic alternative in the treatment of hypertension because of their ACE inhibitory activity and protective effects on oxidative damaged HUVECs.

Funder

National Natural Science Foundation of China

Zhejiang Provincial Ten Thousand Plan for Young Top Talents

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO00275B

Reference69 articles.

1. WHO, World Health Organization , Global health observatory data: Raised blood pressure, situation and trends , 2018

2. New drug targets for hypertension: A literature review