Transition metal-free direct dehydrogenative arylation of activated C(sp3)–H bonds: synthetic ambit and DFT reactivity predictions-Reference-Cited by-同舟云学术

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Transition metal-free direct dehydrogenative arylation of activated C(sp3)–H bonds: synthetic ambit and DFT reactivity predictions

Published:2018 Issue:41 Volume:9 Page:7992-7999
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Lovato Kaitlyn¹²³⁴⁵^ORCID,Guo Lirong⁶⁷⁸⁹¹⁰,Xu Qing-Long¹¹¹²¹³¹⁴¹⁰^ORCID,Liu Fengting⁶⁷⁸⁹¹⁰,Yousufuddin Muhammed¹⁵¹⁶¹⁷⁵,Ess Daniel H.¹⁸¹⁹²⁰⁵,Kürti László¹²³⁴⁵^ORCID,Gao Hongyin⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Department of Chemistry

2. Rice University

3. BioScience Research Collaborative

4. Houston

5. USA

6. Ministry of Education Key Laboratory of Colloid and Interface Chemistry

7. School of Chemistry and Chemical Engineering

8. Shandong University

9. Ji'nan 250100

10. China

11. Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease

12. State Key Laboratory of Natural Medicines

13. China Pharmaceutical University

14. Nanjing 210009

15. Life and Health Sciences Department

16. The University of North Texas at Dallas

17. Dallas

18. Department of Chemistry and Biochemistry

19. Brigham Young University

20. Provo

Abstract

A direct and general mono-arylation of activated C(sp³)–H bonds with nitroarenes under transition metal-free conditions has been developed.

Funder

Division of Chemistry

National Institute of General Medical Sciences

Division of Graduate Education

National Natural Science Foundation of China

Welch Foundation

Amgen

Shandong University

Natural Science Foundation of Shandong Province

Rice University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SC/C8SC02758G

Reference59 articles.

1. G. Brahmachari , in Chemistry and Pharmacology of Naturally Occuring Bioactive Compounds , ed. G. Brahmachari , CRC Press , Boca Raton, FL , 2013 , ch. 4, p. 98

2. L. A. M. Daniel Lednicer , in The Organic Chemistry of Drug Synthesis , Wiley , New York , 1980 , vol. 2 , pp. 63–84

3. Verapamil analog with restricted molecular flexibility

4. Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

5. Twenty Years of Naproxen Technology

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