Visible-light-induced hydroxycarboxylation of α-trifluoromethylstyrenes to construct densely functionalized α-CF<sub>3</sub> tertiary alcohols-Reference-Cited by-同舟云学术

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Visible-light-induced hydroxycarboxylation of α-trifluoromethylstyrenes to construct densely functionalized α-CF₃ tertiary alcohols

Published:2024 Issue:15 Volume:26 Page:8694-8700
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Lu Min-Ming¹,Deng Ning²,Li Shi-Yu¹,Tong Ren-Jie¹,Xu Jun¹^ORCID,Xu Hua-Jian¹²^ORCID

Affiliation:

1. School of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, P. R. China

2. School of Chemistry and Chemical Engineering, Anhui Province Key Laboratory of Advance Catalytic Materials and Reaction Engineering, Hefei University of Technology, Hefei, 230009, P. R. China

Abstract

Visible-light-induced hydroxycarboxylation of α-trifluoromethylstyrenes under an air atmosphere was developed to construct densely functionalized α-CF3 tertiary alcohols.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/GC/D4GC01676A

Reference82 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

3. Applications of Fluorine in Medicinal Chemistry

4. Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

5. Validating the 1,2-Difluoro Motif As a Hybrid Bioisostere of CF3 and Et Using Matrix Metalloproteinases As Structural Probes

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