Selective synthesis of spirooxindoles via a two-step reaction of N-phenacylpyridinium bromide, 1,3-indanedione and N-alkylisations

Abstract

The three-component reaction resulted in the unique spiro[indoline-3,4′-naphtho[1,2-b]furan] derivatives, which were converted to spiro[indoline-3,2′-naphthalen]-4′-yl acetates by acylation and alkoxy-substituted spiro[benzo[h]chromene-5,3′-indolines] by acid catalyzed etherification.