Genome mining reveals a new cyclopentane-forming sesterterpene synthase with unprecedented stereo-control-Reference-Cited by-同舟云学术

Genome mining reveals a new cyclopentane-forming sesterterpene synthase with unprecedented stereo-control

Published:2022 Issue:21 Volume:9 Page:5808-5818
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Qiao Yuben¹^ORCID,Xu Qiaoxin¹,Huang Zijian¹,Chen Xia²,Ren Xiaomeng¹,Yuan Wenling¹,Guan Zhenhua¹,Li Pengkun¹,Li Fengli¹,Xiong Chaomei¹,Zhu Hucheng¹,Chen Chunmei¹,Gu Lianghu¹,Zhou Yuan¹^ORCID,Qi Changxing¹,Hu Zhengxi¹^ORCID,Liu Junjun¹^ORCID,Ye Ying¹,Zhang Yonghui¹^ORCID

Affiliation:

1. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China

2. National & Local Joint Engineering Research Center of High-Throughput Drug Screening Technology, Hubei Key Laboratory of Biotechnology of Chinese Traditional Medicine, School of Life Sciences, Hubei University, Wuhan, 430062, China

Abstract

Fungal bifunctional terpene synthase PstA catalyzes the formation of 5/15 cis-fused ring system.

Funder

National Key Research and Development Program of China

Changjiang Scholar Program of Chinese Ministry of Education

National Science Fund for Distinguished Young Scholars

National Science and Technology Planning Project

National Natural Science Foundation of China

Postdoctoral Science Foundation of Hubei Province

China Postdoctoral Science Foundation

Fundamental Research Funds for the Central Universities

Publisher