Focused Genome Mining of Structurally Related Sesterterpenes: Enzymatic Formation of Enantiomeric and Diastereomeric Products

Author:

Narita Koji1,Sato Hajime234,Minami Atsushi1,Kudo Kosei1,Gao Lei15,Liu Chengwei1,Ozaki Taro1,Kodama Motoichiro6,Lei Xiaoguang5ORCID,Taniguchi Tohru7ORCID,Monde Kenji7ORCID,Yamazaki Mami4,Uchiyama Masanobu23ORCID,Oikawa Hideaki1ORCID

Affiliation:

1. Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan

2. Elements Chemistry Laboratory, RIKEN, and RIKEN Center for Sustainable Resource Science (Wako campus), Saitama 351-0198, Japan

3. Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan

4. Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan

5. Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

6. Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan

7. Faculty of Advanced Life Science, Frontier Research Center for Post-Genome Science and Technology, Hokkaido University, Sapporo 060-0810, Japan

Funder

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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