Molecular recognition of bio-active flavonoids quercetin and rutin by bovine hemoglobin: an overview of the binding mechanism, thermodynamics and structural aspects through multi-spectroscopic and molecular dynamics simulation studies

Author:

Das Sourav1234,Bora Nikita5674,Rohman Mostofa Ataur819104,Sharma Raju1234,Jha Anupam Nath5674,Singha Roy Atanu1234ORCID

Affiliation:

1. Department of Chemistry

2. National Institute of Technology

3. Shillong 793003

4. India

5. Department of Molecular Biology and Biotechnology

6. Tezpur University

7. Tezpur 784028

8. Centre for Advanced Studies

9. North-Eastern Hill University

10. Shillong 793022

Abstract

A spectroscopic and computational analysis of the interactions of two bio-active flavonoids with bovine hemoglobin (BHb) has been carried out.

Funder

Science and Engineering Research Board

Department of Biotechnology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

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