Combinatorial synthesis and biological evaluations of (E)-β-trifluoromethyl vinylsulfones as antitumor agents-Reference-Cited by-同舟云学术

Combinatorial synthesis and biological evaluations of (E)-β-trifluoromethyl vinylsulfones as antitumor agents

Published:2019 Issue:54 Volume:9 Page:31474-31482
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tang Haosha¹²³⁴,Kuang Yunyan⁵²⁶⁴,Zeng Julan⁵⁷⁸⁴,Li Xiaofang⁹¹⁰¹¹⁴,Zhou Wei⁵²⁶⁴^ORCID,Lu Yuan¹²³⁴

Affiliation:

1. Obstetrics and Gynecology Hospital

2. Fudan University

3. Shanghai 200011

4. China

5. Department of Chemistry

6. Shanghai 200433

7. Changsha University of Science and Technology

8. Changsha 410114

9. School of Chemistry and Chemical Engineering

10. Hunan University of Science and Technology

11. Xiangtan 411201

Abstract

(E)-β-Trifluoromethyl vinylsulfones is accomplished through a reaction of alkynes, Togni reagent, and sodium benzenesulfinates under metal-free conditions. p-Acetylphenyl in R¹ has the best activities against several tumor cells.

Funder

Science and Technology Commission of Shanghai Municipality

Fudan University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA06368D

Reference70 articles.

1. Organotellurium catalysis-enabled utilization of molecular oxygen as oxidant for oxidative deoximation reactions under solvent-free conditions

2. Visible light-promoted, iodine-catalyzed selenoalkoxylation of olefins with diselenides and alcohols in the presence of hydrogen peroxide/air oxidant: an efficient access to α-alkoxyl selenides

3. Synthesis of 3-(Organochalcogen) Chalcogenazolo Indoles via Cascade Cyclization of N-Alkynylindoles

4. Metal-free difunctionalization of alkynes leading to alkenyl dithiocyanates and alkenyl diselenocyanates at room temperature

5. A Benzoyl Peroxide/Diphenyl Diselenide Binary System for Functionalization of Alkynes Leading to Alkenyl and Alkynyl Selenides

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent Progress in Synthetic Applications of Hypervalent Iodine(III) Reagents;Chemical Reviews;2024-09-13

2. A bioactive sprite: Recent advances in the application of vinyl sulfones in drug design and organic synthesis;Life Sciences;2024-09

3. Silver Nitrate Catalyzed Sulfonylation of O-Propargyl Alkynes;Synlett;2023-11-07

4. Recent Progress in Synthetic Applications of Cyclic Hypervalent Iodine(III) Reagents;Advanced Synthesis & Catalysis;2023-05-03

5. Recent applications of vinyl sulfone motif in drug design and discovery;European Journal of Medicinal Chemistry;2022-04