Late-stage difluoromethylation: concepts, developments and perspective-Reference-Cited by-同舟云学术

Late-stage difluoromethylation: concepts, developments and perspective

Published:2021 Issue:14 Volume:50 Page:8214-8247
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Sap Jeroen B. I.¹²³⁴⁵^ORCID,Meyer Claudio F.¹²³⁴⁵^ORCID,Straathof Natan J. W.¹²³⁴⁵,Iwumene Ndidi¹²³⁴⁵,am Ende Christopher W.⁶⁷⁸⁹,Trabanco Andrés A.¹⁰¹¹¹²¹³^ORCID,Gouverneur Véronique¹²³⁴⁵^ORCID

Affiliation:

1. Chemistry Research Laboratory

2. Department of Chemistry

3. Oxford University

4. OX1 3TA Oxford

5. UK

6. Pfizer Inc.

7. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, and 1 Portland Street

8. Cambridge

9. USA

10. Discovery Chemistry

11. Janssen Research and Development

12. 45007 Toledo

13. Spain

Abstract

This review describes the conceptual advances that have led to the multiple difluoromethylation processes making use of well-defined CF₂H sources.

Funder

Engineering and Physical Sciences Research Council

Pfizer

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CS/D1CS00360G

Reference211 articles.

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