Copper-catalyzed aerobic double functionalization of benzylic C(sp3)–H bonds for the synthesis of 3-hydroxyisoindolinones-Reference-Cited by-同舟云学术

Copper-catalyzed aerobic double functionalization of benzylic C(sp3)–H bonds for the synthesis of 3-hydroxyisoindolinones

Published:2021 Issue:69 Volume:57 Page:8604-8607
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Nozawa-Kumada Kanako¹^ORCID,Matsuzawa Yuta¹,Ono Kanako¹,Shigeno Masanori¹^ORCID,Kondo Yoshinori¹^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan

Abstract

A copper-catalyzed aerobic 3-hydroxyisoindolinone synthesis was developed via the benzylic double C(sp3)–H functionalization of 2-alkylbenzamides.

Funder

Japan Society for the Promotion of Science

Takahashi Industrial and Economic Research Foundation

Takeda Science Foundation

TOBE MAKI Scholarship Foundation

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC02870G

Reference45 articles.

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2. sp3 C–H oxidation by remote H-radical shift with oxygen- and nitrogen-radicals: a recent update

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4. Statistical Investigation into the Structural Complementarity of Natural Products and Synthetic Compounds

5. Making carbon-nitrogen bonds in biological and chemical synthesis

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