Carbene and photocatalyst-catalyzed 3-acylation of indoles for facile access to indole-3-yl aryl ketones-Reference-Cited by-同舟云学术

Carbene and photocatalyst-catalyzed 3-acylation of indoles for facile access to indole-3-yl aryl ketones

Published:2024 Issue: Volume: Page:
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Tu Ting¹,Nie GuiHua¹,Zhang Tinglei¹,Hu ChunMei¹,Ren Shi-Chao¹^ORCID,Xia Huimin²,Chi Yonggui Robin¹³^ORCID

Affiliation:

1. State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang, 550025, China

2. School of Pharmaceutical Science, Guizhou University, Guiyang, 550025, China

3. School of Chemistry, Chemical Engineering, and Biotechnology, Nanyang Technological University, Singapore 637371, Singapore

Abstract

A carbene and photocatalyst-catalyzed 3-acylation of indoles was disclosed, providing access to indole-3-yl aryl ketones, which play important roles in both organic synthesis and diverse types of functional molecules.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Guizhou Provincial Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC03257H

Reference35 articles.

1. Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach

2. Substituted Pyrrol-1-ylacetic Acids That Combine Aldose Reductase Enzyme Inhibitory Activity and Ability To Prevent the Nonenzymatic Irreversible Modification of Proteins from Monosaccharides

3. A convenient synthesis of 3-acylindoles via Friedel Crafts acylation of 1-(phenylsulfonyl)indole. A new route to pyridocarbazole-5,11-quinones and ellipticine

4. A General Method for Acylation of Indoles at the 3-Position with Acyl Chlorides in the Presence of Dialkylaluminum Chloride