Stereogenic and conformational properties of medium-ring benzo-fused N-heterocycle atropisomers-Reference-Cited by-同舟云学术

Stereogenic and conformational properties of medium-ring benzo-fused N-heterocycle atropisomers

Published:2021 Issue:33 Volume:19 Page:7098-7115
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

de Ceuninck van Capelle Lillian A.¹^ORCID,Macdonald James M.²,Hyland Christopher J. T.¹^ORCID

Affiliation:

1. Molecular Horizons Research Institute, School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, New South Wales, 2522, Australia

2. CSIRO Manufacturing, Biomedical Manufacturing Program, Bag 10, Clayton South, Victoria, 3169, Australia

Abstract

By examining the various contributions to the conformational and stereogenic stability of medium-sized benzo-fused N-heterocyclic atropisomers, this review serves to aid the design, synthesis and study of these pharmaceutically relevant heterocycles.

Funder

Commonwealth Scientific and Industrial Research Organisation

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00836F

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