Modified cyclodextrins solubilize elemental sulfur in water and enable biological sulfane sulfur delivery-Reference-Cited by-同舟云学术

Modified cyclodextrins solubilize elemental sulfur in water and enable biological sulfane sulfur delivery

Published:2020 Issue:43 Volume:11 Page:11777-11784
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Bolton Sarah G.¹²³⁴⁵^ORCID,Pluth Michael D.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry

2. Materials Science Institute

3. Knight Campus for Accelerating Scientific Impact

4. Institute of Molecular Biology

5. University of Oregon

Abstract

Sulfane sulfur, or S⁰, is found in polysulfide and persulfide compounds in biology. We demonstrate that modified cyclodextrins can solubilize S₈ in water, increase its reactivity with biological nucleophiles, and enable delivery to live cells.

Funder

National Institutes of Health

National Science Foundation

Camille and Henry Dreyfus Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC04137H

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