Facile carbohydrate-mimetic modifications of poly(ethylene imine) carriers for gene delivery applications

Author:

Englert Christoph12345,Fevre Mareva123,Wojtecki Rudy J.123ORCID,Cheng Wei678,Xu Qingxing678,Yang Chuan678,Ke Xiyu678,Hartlieb Matthias4591011,Kempe Kristian4591011,García Jeannette M.123,Ono Robert J.123,Schubert Ulrich S.4591011,Yang Yi Yan678,Hedrick James L.123

Affiliation:

1. IBM Almaden Research Center

2. San Jose

3. USA

4. Laboratory of Organic and Macromolecular Chemistry (IOMC)

5. Friedrich Schiller University Jena

6. Institute of Bioengineering and Nanotechnology

7. Singapore 138669

8. Singapore

9. 07743 Jena

10. Germany

11. Jena Center for Soft Matter (JCSM)

Abstract

PEI was chemically-modified with carbohydrates and carbohydrate-mimetics to improve biocompatibility.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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