Evaluation of the inhibitory potential of HPMC, PVP and HPC polymers on nucleation and crystal growth
Author:
Affiliation:
1. Solid State Pharmaceutical Research Group (SSPRG)
2. Department of Pharmaceutics
3. National Institute of Pharmaceutical Education and Research (NIPER)
4. Hyderabad
5. India
Abstract
Supersaturated drug delivery systems are generally developed for improving solubility and dissolution of poorly soluble drugs.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA19746A
Reference27 articles.
1. Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?
2. Drug precipitation inhibitors in supersaturable formulations
3. Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility
4. Use of a screening method to determine excipients which optimize the extent and stability of supersaturated drug solutions and application of this system to solid formulation design
5. Understanding the Behavior of Amorphous Pharmaceutical Systems during Dissolution
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