A concise synthesis and biological study of evodiamine and its analogues

Author:

Deng Jie-Dan12342,Lei Shuai123,Jiang Yi123ORCID,Zhang Hong-Hua123,Hu Xiao-Ling123,Wen Huai-Xiu567,Tan Wen123,Wang Zhen12342ORCID

Affiliation:

1. School of Pharmacy, Lanzhou University

2. Lanzhou 730000

3. China

4. Institution State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University

5. Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences

6. Xining

7. P. R. China

Abstract

Efficient access to evodiamine and its analogues is presented via Lewis acid catalysis. In this reaction, three chemical bonds and two heterocyclic-fused rings are constructed in one step.

Funder

Recruitment Program of Global Experts

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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