Colchicine metallocenyl bioconjugates showing high antiproliferative activities against cancer cell lines-Reference-Cited by-同舟云学术

Colchicine metallocenyl bioconjugates showing high antiproliferative activities against cancer cell lines

Published:2017 Issue:48 Volume:46 Page:17041-17052
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Kowalczyk Karolina¹²³⁴⁵^ORCID,Błauż Andrzej⁶⁷⁸³⁹^ORCID,Ciszewski Wojciech M.¹²³⁴⁵^ORCID,Wieczorek Anna¹²³⁴⁵^ORCID,Rychlik Błażej⁶⁷⁸³⁹^ORCID,Plażuk Damian¹²³⁴⁵^ORCID

Affiliation:

1. Department of Organic Chemistry

2. Faculty of Chemistry

3. University of Łódź

4. 91-403 Łódź

5. Poland

6. Cytometry Lab

7. Department of Molecular Biophysics

8. Faculty of Biology and Environmental Protection

9. 90-236 Łódź

Abstract

Ferrocenyl and ruthenocenyl conjugates with colchicine have been synthesised and their cytotoxic activity, influence on the cell cycle, and interactions with tubulin were evaluated.

Funder

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/DT/C7DT03229C

Reference47 articles.

1. Colchicine for the treatment of gout

2. Colchicine poisoning: the dark side of an ancient drug

3. Synthesis and SAR requirements of adamantane–colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities