Design, Synthesis, and Antitumor Activity of 4-Halocolchicines and Their Pro-drugs Activated by Cathepsin B
Author:
Affiliation:
1. Graduate School of Pharmaceutical Sciences, Chiba University
2. Yakult Central Institute for Microbiological Research
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ml100287y
Reference26 articles.
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4. Biological effects of modified colchicines. Improved preparation of 2-demethylcolchicine, 3-demethylcolchicine, and (+)-colchicine and reassignment of the position of the double bond in dehydro-7-deacetamidocolchicines
5. New Synthetic Thiocolchicine Derivatives as Lowtoxic Anticancer Agents
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