The pharmacokinetics, bioavailability and excretion of columbianetin acetate and its metabolite columbianetin were analysed in rat plasma by LC-MS/MS after administration of columbianetin acetate and Angelicae pubescentis radix extract
Author:
Affiliation:
1. Tianjin State Key Laboratory of Modern Chinese Medicine
2. Tianjin University of Traditional Chinese Medicine
3. Tianjin
4. China
5. Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis
Abstract
Angelicae pubescentis radix (APR) has been widely used in the clinic for the treatment of rheumatoid arthritis.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA13961A
Reference27 articles.
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3. Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats
4. Appraisal of clinical practice guidelines for the management of rheumatoid arthritis in traditional Chinese medicine using the AGREE II instrument: A systematic review
5. Chinese herbal medicines versus disease modifying antirheumatic drugs for management of rheumatoid arthritis: A systematic review
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1. Comparison of Pharmacokinetic Profiles of 14 Major Bioactive Components in Normal and Arthritic Model Rats after Oral Administration of Angelicae pubescentis Radix by UPLC-MS/MS;Evidence-Based Complementary and Alternative Medicine;2022-08-16
2. A novel method for investigating the mechanism of the anti‐rheumatoid arthritis activity of Angelicae pubescentis radix by integrating UHPLC–QTOF/MS and network pharmacology;Biomedical Chromatography;2022-05-07
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5. Traditional Chinese Medicine of Angelicae Pubescentis Radix: A Review of Phytochemistry, Pharmacology and Pharmacokinetics;Frontiers in Pharmacology;2020-03-18
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