Natural product and natural product derived drugs in clinical trials-Reference-Cited by-同舟云学术

Natural product and natural product derived drugs in clinical trials

Published:2014 Issue:11 Volume:31 Page:1612-1661
ISSN:0265-0568
Container-title:Nat. Prod. Rep.
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Butler Mark S.¹²³⁴,Robertson Avril A. B.¹²³⁴,Cooper Matthew A.¹²³⁴

Affiliation:

1. Division of Chemistry and Structural Biology

2. Institute for Molecular Bioscience

3. The University of Queensland

4. Brisbane, Australia

Abstract

The 25 Natural Product (NP)-derived drugs launched since 2008 and the 100 NP-derived compounds and 33 Antibody Drug Conjugates (ADCs) in clinical trials or in registration at the end of 2013 are reviewed.

Funder

Wellcome Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/NP/C4NP00064A

Reference616 articles.

1. Clinical development success rates for investigational drugs

2. Decline in new drug launches: myth or reality? Retrospective observational study using 30 years of data from the UK

3. Financial Aspects and the Future of the Pharmaceutical Industry in the United States of America

4. The Role of Natural Product Chemistry in Drug Discovery

5. The evolving role of natural products in drug discovery

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