Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth-Reference-Cited by-同舟云学术

Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth

Published:2017 Issue:34 Volume:9 Page:12709-12717
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Bhattacharyya Jayanta¹²³⁴,Ren Xiu-Rong⁵⁶³⁴,Mook Robert A.⁵⁶³⁴,Wang Jiangbo⁵⁶³⁴,Spasojevic Ivan⁷⁸³⁴,Premont Richard T.⁵⁶³⁴^ORCID,Li Xinghai¹²³⁴,Chilkoti Ashutosh¹²³⁴^ORCID,Chen Wei⁵⁶³⁴

Affiliation:

1. Department of Biomedical Engineering

2. Duke University

3. Durham

4. USA

5. Department of Medicine

6. Duke University Medical Center

7. Duke Cancer Institute

8. PK/PD Core Laboratory

Abstract

Attachment of the hydrophobic drug NIC (purple triangles) to CP (black chains) triggers self-assembly into cylindrical nanoparticles.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NR/C7NR01973D

Reference62 articles.

1. Mining the Wnt pathway for cancer therapeutics

2. Wnt Signaling in Development, Disease and Translational Medicine

3. Cancer Stem Cells: The Emerging Challenge of Drug Targeting

4. Discovery of Modulators of Protein-Protein Interactions: Current Approaches and Limitations

5. The Anti-Helminthic Niclosamide Inhibits Wnt/Frizzled1 Signaling

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