Photoredox-enabled 1,2-dialkylation of α-substituted acrylates via Ireland–Claisen rearrangement-Reference-Cited by-同舟云学术

Photoredox-enabled 1,2-dialkylation of α-substituted acrylates via Ireland–Claisen rearrangement

Published:2021 Issue:8 Volume:12 Page:2816-2822
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kleinmans Roman¹²³⁴,Will Leon E.¹²³⁴,Schwarz J. Luca¹²³⁴,Glorius Frank¹²³⁴^ORCID

Affiliation:

1. Organisch-Chemisches Institut

2. Westfälische Wilhelms-Universität Münster

3. 48149 Münster

4. Germany

Abstract

A photocatalytic 1,2-dialkylation of α-substituted acrylates is enabled by a reaction cascade combining reductive radical-polar crossover with the established Ireland–Claisen rearrangement for the synthesis of valuable tertiary carboxylic acids.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D0SC06385A

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