Global profiling of cellular targets of gambogic acid by quantitative chemical proteomics-Reference-Cited by-同舟云学术

Global profiling of cellular targets of gambogic acid by quantitative chemical proteomics

Published:2016 Issue:97 Volume:52 Page:14035-14038
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Zhou Yiqing¹²³⁴⁵^ORCID,Li Weichao¹²³⁴⁵,Zhang Xixi⁶⁷⁸⁹⁴,Zhang Haibing⁹⁴⁵¹⁰⁸,Xiao Youli¹²³⁴⁵

Affiliation:

1. CAS Key Laboratory of Synthetic Biology

2. CAS Centre for Excellence in Molecular Plant Sciences

3. Institute of Plant Physiology and Ecology

4. Shanghai Institutes for Biological Sciences

5. Chinese Academy of Sciences

6. University of Chinese Academy of Sciences

7. Beijing 100039

8. China

9. Institute for Nutritional Sciences

10. Shanghai 200032

Abstract

Gambogic acid has shown significant potential as an anti-cancer and anti-inflammatory compound, here we report that the target profiling of gambogic acid in human cancer cells via quantitative chemical proteomics.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC07581A

Reference25 articles.

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2. Garcinia Xanthones as Orally Active Antitumor Agents

3. New targets for the antitumor activity of gambogic acid in hematologic malignancies

4. General pharmacological properties, developmental toxicity, and analgesic activity of gambogic acid, a novel natural anticancer agent

5. A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid

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