Protein corona in drug delivery for multimodal cancer therapy in vivo-Reference-Cited by-同舟云学术

Protein corona in drug delivery for multimodal cancer therapy in vivo

Published:2018 Issue:5 Volume:10 Page:2461-2472
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Yeo Eugenia Li Ling¹²³^ORCID,Thong Patricia Soo Ping⁴⁵⁶⁷^ORCID,Soo Khee Chee⁴⁵⁶⁷,Kah James Chen Yong¹²³⁴⁵^ORCID

Affiliation:

1. Department of Biomedical Engineering

2. National University of Singapore

3. Singapore 117583

4. Division of Medical Sciences

5. National Cancer Centre Singapore

6. 11 Hospital Drive

7. Singapore 169610

Abstract

Intravenous delivery of NR-MS-Ce6, wherein Ce6 was loaded on NRs using a protein corona formed from mouse serum, resulted in tumor accumulation and synergy between PTT and PDT, leading to enhanced therapeutic efficacy and complete tumor regression in 19 days.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NR/C7NR08509E

Reference84 articles.

1. Biomolecular coronas provide the biological identity of nanosized materials

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4. Protein corona significantly reduces active targeting yield

5. Optimization of PEGylation Conditions for BSA Nanoparticles Using Response Surface Methodology

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