Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface-Reference-Cited by-同舟云学术

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

Published:2013-01-20 Issue:2 Volume:8 Page:137-143
ISSN:1748-3387
Container-title:Nature Nanotechnology
language:en
Short-container-title:Nature Nanotech

Author:

Salvati Anna,Pitek Andrzej S.,Monopoli Marco P.,Prapainop Kanlaya,Bombelli Francesca Baldelli,Hristov Delyan R.,Kelly Philip M.,Åberg Christoffer,Mahon Eugene,Dawson Kenneth A.

Publisher

Springer Science and Business Media LLC

Subject

Electrical and Electronic Engineering,Condensed Matter Physics,General Materials Science,Biomedical Engineering,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://www.nature.com/articles/nnano.2012.237.pdf

Reference35 articles.

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2. Ferrari, M. Cancer nanotechnology: opportunities and challenges. Nature Rev. Cancer 5, 161–171 (2005).

3. Cedervall, T. et al. Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc. Natl Acad. Sci. USA 104, 2050–2055 (2007).

4. Nel, A. E. et al. Understanding biophysicochemical interactions at the nano–bio interface. Nature Mater. 8, 543–557 (2009).

5. Hrkach, J. et al. Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile. Sci. Transl. Med. 4, 128–139 (2012).

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