The anti-fatigue effect of the Auxis thazard oligopeptide via modulation of the AMPK/PGC-1α pathway in mice

Author:

Qu Yushan1ORCID,Ji Hongwu12345,Song Wenkui1,Peng Shuo1,Zhan Suhong1,Wei Liuyi1ORCID,Chen Ming1,Zhang Di1,Liu Shucheng12345

Affiliation:

1. College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, P.R. China

2. Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Zhanjiang 524088, P.R. China

3. Guangdong Province Engineering Laboratory for Marine Biological Products, Zhanjiang 524088, P.R. China

4. Guangdong Provincial Engineering Technology Research Center of Marine Food, Zhanjiang 524088, P.R. China

5. Key Laboratory of Advanced Processing of Aquatic Product of Guangdong Higher Education Institution, Zhanjiang 524088, P.R. China

Abstract

The anti-fatigue effect of the ATO has been confirmed for the first time and its mechanism was revealed from the modulation of the oxidative stress and AMPK/PGC-1α pathway in mice.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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