Functionalised bicyclic tetramates derived from cysteine as antibacterial agents

Author:

Panduwawala Tharindi D.12345,Iqbal Sarosh12345,Thompson Amber L.12345ORCID,Genov Miroslav67895,Pretsch Alexander67895,Pretsch Dagmar67895,Liu Shuang10111213,Ebright Richard H.10111213,Howells Alison141516175,Maxwell Anthony181916205,Moloney Mark G.12345ORCID

Affiliation:

1. Department of Chemistry

2. Chemistry Research Laboratory

3. University of Oxford

4. Oxford

5. UK

6. Oxford Antibiotic Group

7. The Oxford Science Park

8. Magdalen Centre

9. Oxford OX4 4GA

10. Waksman Institute and Department of Chemistry

11. Rutgers University

12. Piscataway

13. USA

14. Inspiralis Limited

15. Innovation Centre

16. Norwich Research Park

17. Norwich NR4 7GJ

18. Dept. Biological Chemistry

19. John Innes Centre

20. Norwich NR4 7UH

Abstract

Carboxamido tetramates derived from a bicyclic skeleton provide access to compounds with antibacterial activity.

Funder

Medical Research Council

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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