Synthesis of reverse glycosyl fluorides via organophotocatalytic decarboxylative fluorination of uronic acids

Author:

Ding Han1ORCID,Yan Ningjie1,Wang Peng1,Song Ni1,Sun Qikai1,Li Tiantian1,Li Ming12ORCID

Affiliation:

1. Key Laboratory of Marine Medicine, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, P. R. China

2. Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology, Qingdao 266237, P. R. China

Abstract

Mes-Acr*-catalyzed decarboxylative fluorination of structurally diverse uronic acids under blue light irradiation provides an alternative avenue for the synthesis of reverse glycosyl fluorides of medicinal and biological relevance.

Funder

National Natural Science Foundation of China-Shandong Joint Fund

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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