Biosynthesis of the Fluorinated Natural Product Nucleocidin inStreptomyces calvusIs Dependent on thebldA-Specified Leu-tRNAUUAMolecule

Author:

Zhu Xi Ming1,Hackl Stefanie2,Thaker Maulik N.3,Kalan Lindsay3,Weber Claudia4,Urgast Dagmar S.4,Krupp Eva M.4,Brewer Alyssa1,Vanner Stephanie1,Szawiola Anjuli1,Yim Grace3,Feldmann Jörg4,Bechthold Andreas2,Wright Gerard D.3,Zechel David L.1

Affiliation:

1. Department of Chemistry; Queen's University; Chernoff Hall 90 Bader Lane Kingston Ontario K7L 3N6 Canada

2. Department of Pharmaceutical Biology and Biotechnology; Institute of Pharmaceutical Sciences; Albert-Ludwigs-Universität Freiburg; Stefan-Meier-Strasse 19 79104 Freiburg Germany

3. Michael G. DeGroote Institute for Infectious Disease Research; McMaster University; 1200 Main Street West Hamilton Ontario L8N 3Z5 Canada

4. Trace Element Speciation Laboratory; Department of Chemistry; University of Aberdeen; Aberdeen AB24 3UE UK

Funder

Natural Sciences and Engineering Research Council

DFG

EU Erasmus Fund

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

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