Synthesis of acridinones via palladium-catalyzed reductive annulation of 2-nitrobenzaldehydes and resorcinols-Reference-Cited by-同舟云学术

Synthesis of acridinones via palladium-catalyzed reductive annulation of 2-nitrobenzaldehydes and resorcinols

Published:2022 Issue: Volume: Page:
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Xie Rong¹,Mao Wenhui¹,Jia Huanhuan¹,Lu Guangpeng¹,Sun Jialu¹,Jiang Huanfeng¹^ORCID,Zhao He¹,Zhang Min¹²^ORCID

Affiliation:

1. Key Lab of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Wushan Rd-381, Guangzhou 510641, People's Republic of China

2. Qingyuan Huayuan Institute of Science and Technology Collaborative Innovation Co., Ltd., China

Abstract

Through a palladium-catalyzed reductive annulation reaction of resorcinols and 2-nitrobenzaldehydes, reported is a new synthesis of acridinones with the features of operational simplicity, broad substrate scope, and readily available feedstocks.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D1QO01693H

Reference55 articles.

1. Synthesis, Antitumor Activity, and Mechanism of Action of Benzo[a]pyrano[3,2-h]acridin-7-one Analogues of Acronycine

2. Synthesis and evaluation of acridine- and acridone-based anti-herpes agents with topoisomerase activity

3. Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation

4. One-Pot Ullmann C-N Coupling Cyclization Toward Domino Synthesis of Fused Hexacyclic Quinolinotriazoloacridinones Catalyzed by CuI/L-Proline

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