TEMPO-catalyzed synthesis of 5-substituted isoxazoles from propargylic ketones and TMSN3-Reference-Cited by-同舟云学术

TEMPO-catalyzed synthesis of 5-substituted isoxazoles from propargylic ketones and TMSN3

Published:2016 Issue:64 Volume:6 Page:58988-58993
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

He Yan¹²³⁴,Xie Yu-yang¹²³⁴,Wang Ying-chun⁵⁶⁷⁴,Bin Xiao-min¹²³⁴,Hu Da-chao¹²³⁴,Wang Heng-shan¹²³⁴,Pan Ying-ming¹²³⁴

Affiliation:

1. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources

2. School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University

3. Guilin 541004

4. People's Republic of China

5. College of Chemistry and Chemical Engineering

6. Jishou University

7. Jishou 416000

Abstract

A novel and efficient TEMPO-catalyzed synthesis of 5-substituted isoxazoles from propargylic ketones and TMSN₃via the radical mechanism process is described. A plausible reaction mechanism for this process is proposed.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA11099A

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