Synthesis and in vitro cytotoxicity of cross-conjugated prostaglandin A and J series and their hydroxy derivatives
Author:
Affiliation:
1. Department of Heteroorganic Chemistry
2. Centre of Molecular and Macromolecular Studies
3. Polish Academy of Sciences
4. 90-363 Łódź
5. Poland
6. Department of Bioorganic Chemistry
Abstract
An efficient synthetic protocol for the synthesis of enantiomerically pure cyclopentenone prostaglandin derivatives is described and the anticancer activity of these derivatives was determined.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00550G
Reference38 articles.
1. Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2. Prostaglandins: physiology, biochemistry, pharmacology and clinical applications
3. Prostaglandins and Inflammation
4. Eicosanoids and cancer
5. PROSTAGLANDINS AND CANCER
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The aldol reaction: Group I and II enolates;Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2024
2. A novel route to a chiral building block for the preparation of cyclopentenyl carbocyclic nucleosides. Synthesis and anticancer activity of enantiomeric neplanocins A;RSC Advances;2020
3. A convenient synthesis of 2,5-diaroyl-4-hydroxy cyclopent-2-enones incorporating aromatic and heteroaromatic moieties;Synthetic Communications;2019-10-14
4. Concise Synthesis of a New Chiral Cyclopentenone Building Block for Prostaglandins and their Derivatives;European Journal of Organic Chemistry;2019-04-12
5. Phosphonate reagents and building blocks in the synthesis of bioactive compounds, natural products and medicines;Pure and Applied Chemistry;2019-02-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3