A novel route to a chiral building block for the preparation of cyclopentenyl carbocyclic nucleosides. Synthesis and anticancer activity of enantiomeric neplanocins A
Author:
Affiliation:
1. Division of Organic Chemistry
2. Centre of Molecular and Macromolecular Studies
3. Polish Academy of Sciences
4. 90-363 Łódź
5. Poland
6. Division of Bioorganic Chemistry
Abstract
A novel route to both enantiomers of a cyclopentene building block was developed and applied to the synthesis of enantiomeric neplanocins A.
Funder
Narodowe Centrum Nauki
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA06394K
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5. Potent and selective activity of a new carbocyclic nucleoside analog (Carbovir: NSC 614846) against human immunodeficiency virus In vitro
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