Paclitaxel-loaded magnetic nanocrystals for tumor neovascular-targeted theranostics: an amplifying synergistic therapy combining magnetic hyperthermia with chemotherapy

Author:

Liu Shuangyu12345,Shi Dongsheng12345,Chen Ling678910,Yan Yu1112135,Wang Xingqi12345,Song Yingying12345,Pu Shengyan12345,Liang Yijun1415165,Zhao Yang678910,Zhang Yu678910ORCID,Xie Jun12345ORCID

Affiliation:

1. Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province

2. School of Life Science

3. Jiangsu Normal University

4. Xuzhou 221116

5. P. R. China

6. State Key Laboratory of Bioelectronics

7. Jiangsu Key Laboratory for Biomaterials and Devices

8. School of Biological Science and Medical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology

9. Southeast University

10. Nanjing 210096

11. Department of Chemistry

12. Bengbu Medical College

13. Bengbu 233030

14. School of Medical engineering

15. Foshan University

16. Foshan 528000

Abstract

Paclitaxel-loaded magnetic nanocrystals are presented as an integrated imaging-mediated diagnostic and targeted magnetic hyperthermia (TMH)-triggered thermochemotherapeutic platform for application in vivo.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions

Natural Science Foundation of Xuzhou City

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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